Native Proteins and Derivatives
Cayman Chemical 3OAcetyl2deoxyadenosIn 2.7mg
A diterpene with antileishmanial and gastroprotective activities induces mortality in L. donovani amastigotes (IC50 0.75 UM) reduces lesion area in a mouse model of hydrochloric acid and ethanol-induced gastric ulcers at 10 mg/kg
Cayman Chemical 2 3-O- 5-ChloronthrnIloy 3.3mg
A JAK3 inhibitor (IC50 11 UM) inhibits FcεRI-mediated LTC4 and LTB4 release from and 5-LO translocation to the membrane in RBL-2H3 mast cells at 10 UM reduces airway hyperresponsiveness and BALF eosinophil infiltration in a mouse model of ovalbumin-induced allergic asthma at 12 and 40 mg/kg
American Research Products Inc Anti FN1 Fibronectin F8 IL12
Anti-Human FN1/Fibronectin (F8-IL12) Research Grade
Cayman Chemical 3OMethylgunosIn5OtrI 2.7mg
A lignan scavenges ABTS radicals in a cell-free assay (IC50 19.4 UM) inhibits LPS-induced NO production in RAW 264.7 macrophages (IC50 84.45 UM) inhibits AB42 self-aggregation in a cell-free assay at 20 UM
Cayman Chemical Rp2DeoxyadenosIn5O 1 2.1mg
An ETA receptor antagonist (Ki 13 nM in rat aortic vascular smooth muscle cells) inhibits ET-1-induced contractions in isolated rat aortic rings and mesenteric microvessels (pA2s 8.1 and 7.97 respectively) decreases systolic blood pressure in DOCA-salt hypertensive rats at 50 mg/kg decreases MAP and LVDP in normotensive pigs at 1 and 5 mg/kg reduces myocardial infarct size as a percentage of the area at risk in a porcine model of LAD coronary artery ligation-induced ischemia-reperfusion injury
Sigma Aldrich Fine Chemicals Biosciences Neutrophil Elastase Activi
Neutrophil Elastase (NE EC 3.4.21.37 leukocyte elastase ELANE ELA2 elastase 2 neutrophil elaszym or serine elastase) is a cytotoxic serine protease. It is stored in the azurophil granules of neutrophil granulocyte and is released following cell stimulation e.g. by pathogens immune complexes or chemotactic agents (PMA). Mutation in the gene ELA2 (neutrophil elastase) results in neutropenia a hereditary disorder characterized by reduced neutrophil count in an individual.
Sigma Aldrich Fine Chemicals Biosciences Thrombospondin 1 human rec
Recombinant human thrombospondin-1 is expressed in HEK293 cells as a glycoprotein with a calculated moleculaer mass of 127.5 kDa. This protein is manufactured in human cells using an all-human production system with no serum. The human cells expression system allows human-like glycosylation and folding and often supports better stability of the protein in culture.
Sigma Aldrich Fine Chemicals Biosciences fibronectin bovine plasma5MG
fibronectin is a glycoprotein with multiple domains. It comprises a N-terminal central binding domain and a heparin-binding domain. Bovine plasma fibronectin has polypeptide chains with disulfide linkage and corresponds to a molecular weight of 220 and 215 kDa.
Cayman Chemical CalpaIn InhIbItr II 25mg
A potent PLD2 inhibitor both in vitro (IC50 140 nM) and in cells (IC50 110 nM) also effective as a PLD1 inhibitor at higher concentrations (IC50 5.1 M in vitro 1.0 M in cells) strongly inhibits the invasive migration of breast cancer cells in transwell assays
Cayman Chemical CalpaIn InhIbItr I 5mg
A bioactive saponin from traditional Chinese medicine dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 23 UM LC50 865 UM) has diverse protective effects for the cardiovascular immune digestive and nervous systems reduces myocardial infarct size in dogs
Biocare Medical, LLC Factor XIIIa Antibody - Concentrate, 1.0 ml
This is a monoclonal antibody to the A-subunit of human coagulation Factor XIII. Studies have shown it recognizes human Factor XIII Achain in both reduced and non-reduced forms. It does not react with human Factor XIII B-chain or human Factor XII. Factor XIII is a betaglobulin found in plasma and is composed of two subunits. Factor XIIIA is the catalytic subunit and is a dimer of M.W. 160,000. According to studies, Factor XIII is present in plasma as an alpha2beta2 heterodimer (M.W. 320,000); whereas in platelets, only the alpha2 unit exists. Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors (3,4). It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system (1-6). Factor XIIIa has also been used with CD34 to differentiate between dermatofibroma and dermatofibrosarcoma protuberans (3).
Abcam Sitagliptin Phosphate Monohydrate, 100MG
MW 523.32 Da, Purity >=98%. Anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose.
The product is subject to the following: Abcam Restricted Use Statement